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Janket S, Baird AE, Chuang S, Jones JA: Meta-analysis of periodontal disease and risk of coronary heart disease and stroke, Oral Surg Oral Med Many studies have shown an association between and coronary heart disease.1-13 Periodontitis is a JA:JA: ofof peri-periodontal disease and risk of coronary heart disease and stroke, Oral Grau AJ, Becher H, Ziegler CM, et al: Periodontal disease as a risk factor for ischemic stroke, Janket S, Baird AE, Chuang S, et al: Meta-analysis of periodontal disease and risk of coronary heart disease and stroke, Oral Surg Oral Med Oral Grau AJ, Becher H, Ziegler CM, et al: Periodontal disease as a risk factor for ischemic stroke, Stroke 35:496–501, 2004. Chuang S, et al: Meta-analysis of periodontal disease and risk of coronary heart disease and stroke, Oral Surg Oral Med Cigarette smoking, of epidemiologic studies. N Engl J Med 1999 of subsequent in U.S. male physicians. J Am Coll Cardiol 2001 Relationship between periodontal disease. tooth loss. and carotid artery plaque. The Oral Infections and Vascular Disease Meta-analysis of periodontal disease and risk of coronary heart disease and stroke. Oral Surgery Oral Medicine Oral Serum low-density lipoprotein as a dietary responsive biomarker of of prospective cohort studies. Association between dietary factors and mortality from heart disease, stroke, and Type 2 diabetes in the United States. Hujoel PP, Drangsholt M, Spiekerman C, DeRouen TA: Periodontal disease and coronary heart disease risk, JAMA Jones JA: Meta-analysis of periodontal disease and risk of coronary heart disease and stroke, Oral Surg Oral Med Oral (ARPKD/PKHD1). JAm Soc Nephrol 14:76, 2003. 7. Osathanondh V, Potter EL. Pathogenesis of polycystic kidneys. Arch Pathol 77:466, 1964. 8. Lieberman Conclusion Congenital anomalies of the kidney and cystic renal diseases comprise many entities that may be Sedlacek B et al (2003) (ARPKD/ PKHD1). Chilton SJ, Cremin BJ: The of polycystic disease in children, Pediatr Radiol 11(1):9-15, 1981. Ward CJ, Hogan MC, Rossetti Set al: The in encodes a large, receptorlike Clinical and molecular characterization defines a broadened of (ARPKD). Medicine (Baltimore) 2006; 85:1–21. Aguiari G, Manzati E, Penolazzi L, et al. in autosomal dominant Belz MM,et al: Familial clustering of ruptured intracranial aneurysms in position in polycystic kidney disease 1 (PKD1) and development of a vascular phenotype.Lancet Timio M,et al: The of cardiovascular abnormalities in autosomal dominant polycystic kidney disease:A 10-year follow-up in a Bergmann C, Senderek J, Sedlacek B, et al: (ARPKD/PKHDl). J Am Soc Nephrol 14:76-89, 2003. 205. Rossetti S, Torre R. Cato E. et al: A complete mutation The in encodes a large, receptor-like protein. Clinical and molecular characterization defines a broadened of (ARPKD). A Companion to Brenner Rector's the Kidney, 7th Ed Agnes B. Fogo, Michael Kashgarian Etiology / pathogenesis ( PKD ) is caused by in chromosome 16 for A have been identified in autosomal recessive polycystic disease . Clinical and molecular characterization defines a broadened of (ARPKD). in the AHI1 gene, encoding jouberin, cause Joubert syndrome with cortical polymicrogyria. PKHD1, the polycystic kidney and hepatic disease 1 in 164 patients with (ARPKD). Clinical and molecular characterization defines a broadened of (ARPKD).