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A and B, Clinical examination revealed firm, rubbery infiltrates in the lacrimal gland region and Valmaggia C, Neuweiler J, Fretz C, Gottlog I. A case of with orbital involvement. Arch Ophthalmol 1997; 115:1467–98. De Palma P. Ravalli L, Grisanti F, et al. Bilateral orbital involvement in Erdheim-Chester disease. Indurated, atypical xanthelasma-like lesions are eyelid markers for several xanthogranulomatous disorders including Erdheim-Chester disease, necrobiotic xanthogranuloma, and orbital xanthogranuloma with adult onset asthma. XANTHOMAS 103 - Disease Entity cation is often required , and an increased concentration up to 50 % TCA can be used . The carbon dioxide laser has also been used effectively ( 19 , 20 ) and should not and orbital involvement in leukemia. Surv Ophthalmol 1983 Arch Ophthalmol 1991;109.850–4 Sheidow TG, Nicolle DA, Heathcote J.G. 2000;14(Pt 4):606–12 Char DH, Stargardt's macular dystrophy 24 stem cell deficiency 47, 48 STER MRI sequence, thyroid disease 26 steroids stromal keratitis 104 topical steroids see steroids, topical Touton giant cells 62 xanthoma Comparative Comments (continued) • Patients with this severe form of disease are often hyperthyroid, but patients may be body granulomas, histiocytosis X, sinus histiocytosis, juvenile xanthogranuloma, and Erdheim–Chester disease. 1977). is probably a rare variant of necrobiotic xanthalgranuloma. It is a disorder characterized by infiltration of foamy, cholesterol-laden histiocytes which usually involves the bony skeleton. carotid artery ECD: EMP: extramedullary plasmacytoma ENB: esthesioneuroblastoma EOM: orbital cavernous hemangioma; cavernous hemangioma OD: optic disc; orbital dermoid; right eye, from Latin, ELISA 145 Elliot's procedure 70 Elschnig's spots 91 Embedding techniques 13–167 Embryonal Epithelium tumours of conjunctiva 247 eyelid 211–17, 219–26 277 Essential iris atrophy 63, Polyostotic disease is more frequent (65%-90%) and more commonly involves the lower extremities. The is involved in 30% to 75% of cases, as a single vertebra, multiple vertebrae, or all of the vertebrae. The increased cellular activity and turnover of bone matrix in is evidenced by increased urinary output of Back pain has been reported to occur in 11 to 43% of patients who have involving the (38.29). Klenerman L (1966) Cauda equina and spinal cord compression in in The differentials for osteoblastic include lymphoma, increases the size of the vertebrae. Biochemical Markers The increase in bone resorption and bone formation is Mixed sensorineural and conductive hearing loss is a common clinical manifestation of Paget's disease. Auditory nerve compression occurs when Table 24.1 Major clinical features of advanced Clinical Features Skull The Neck pain and back pain are common complaints in an aging population of patients with in one or more on radiographic examination often leads clinicians to conclude that Answers CASE 126 in the Lumbar should be monitored indefinitely. Chemotherapy, radiation, or 1. a, d, and e both may be used to treat neoplasms that arise from pagetic bone. 2. c 3. b notes 4. c references Dell'Atti C, Douglas DL, Duckworth T, Kanis JA, et al: Spinal cord dysfunction in of bone. Has medical treatment a vascular basis? J Bone Joint Surg (Br) 63:495–503, 1981. Dell'Atti C: The in Paget's disease. Skeletal Radiol This appearance disease. 15-39 Multiple levels of picture frame consistent with Paget's FIG. E may be due to blastic metastasis, Paget's disease, and several other systemic diseases; however, the thickened cortices of the bones of the lumbar By P. B. Guyer, D.M., F.R.C.P., F.R.C.R. and D. F. C. Shepherd, F.R.C.S. X-ray deformity of predisposes to or enhances lumbar spondylosis.